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Sales of Spinal Muscular Atrophy Market to Cross US$0.47 globally by the end of 2023 Marco Parolo Italy Jersey , reports TMR Health Articles | August 16, 2016

Spinal muscular atrophy (SMA) is a hereditary autosomal recessive disease affecting areas of the nervous system that control voluntary muscle movement. Mutation in survival motor neuron (SMN) gene causes deficiency of SMN protein.



A new report, titled “Spinal Muscular Atrophy Market - Pipeline Assessment, Size, Growth, Trends Manolo Gabbiadini Italy Jersey , and Forecast 2015 - 2023” has been published by Transparency Market Research. The study offers a detailed analysis of the聽spinal muscular atrophy market, providing insights into the pipeline assessment, major growth drivers, restraints, and potential opportunities. According to the research study, the spinal muscular atrophy phase three candidate ISIS-SMNRx is projected to generate revenue of US$0.47 by the end of 2023 in the U.S.聽


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Spinal muscular atrophy is genetic neuromuscular disease that is characterized by muscle weakness and atrophy. This disease is the leading genetic cause of death in toddlers and infants Luca Antonelli Italy Jersey , given that it generally manifests early in life. According to the Spinal Muscular Atrophy Association, this disease affects an estimated 10,000 to 25,000 adults and children in the U.S. alone, making it one of the most common rare diseases. The association reveals that an estimated 6 million Americans are carriers of the SMA gene and one in 6,000 to one in 10 Lorenzo Insigne Italy Jersey ,000 kids are born with this neuromuscular disease.


The research report offers key insights into the prevalence and current treatment pattern of spinal muscular atrophy, identifying major market drivers, opportunities, and restraints in the global market for spinal muscular atrophy therapeutics. An analysis of market attractiveness with respect to geography takes into consideration several factors such as drug pricing policies, current competition intensity, patient population Lorenzo De Silvestri Italy Jersey , regulatory restrictions, and present state of the healthcare sector. This gives readers a clear picture of the potential of each geographical segment of the spinal muscular atrophy market.


The spinal muscular atrophy therapeutics market is segmented into early stage candidates and late stage candidates. Early stage candidates of Phase 1 and Phase 2 include LMI070, CK-2127107, RG3039, Olesoxime (TRO19622), RO6885247 Leonardo Bonucci Italy Jersey , and . Late stage candidates of Phase 3 include ISIS-SMN Rx. This Phase 3 candidate for the treatment of Type 1 and Type 2 SMA is present an annual sales of US$0.4 bn in the US by the end of the forecast period in 2023.


Europe and the US are presently the dominating markets for spinal muscular atrophy therapeutics owing to the fact that these regions have a greater percentage of diagnosed cases of SMA. Private and government organizations have been largely involved in creating awareness about spinal muscular atrophy. In addition, the governments in these regions have been offering incentives for the development of therapeutic options for the treatment of rare diseases, which in turn boosts research and development in the field of spinal muscular atrophy.


The major companies competing in this space are F. Hoffmann-La Roche Ltd., Isis Pharmaceuticals, Inc., AveXis Graziano Pelle Italy Jersey , Inc., Cytokinetics, Inc., and Novartis AG, and these players have been profiled in the report with the help of several market intelligence tools. Their strengths, weaknesses Giorgio Chiellini Italy Jersey , opportunities, and threats have been evaluated, along with a detailed assessment of their product offerings.


Brits moving permanently to Bulgaria


It has been reported that many Brits are falling for Bulgaria 's charms with a growing number choosing to move there permanently. In recent years investment has been the main driving force behind the number of Brits buying property in the country but many have decided to buy and live outside the Sunny Beach area and a few miles inland as well as other village areas around the country.


There are a number of factors for those choosing to move but the low cost of living and the seemingly peaceful surrounds are the most likely reasons so many Brits are making the move. Many have also been able to rent out there properties back in the UK , and live very comfortably off the rental income in Bulgaria .


As more companies relocate to Bulgaria to take advantage of the low wages and to strategically place themselves for the countries' expected accession to the EU in 2007, many British employees are expected to relocate with their employers. Tourist areas have seen recent year-on-year growth of between 25% up to as much as 100% however those opting to live in to move permanently prefer to be based inland.


Many Brits are buying around the Veliko Turnovo region with home prices starting as low as GBP 10,000. There are still cheaper homes available however many will require additional funds to provide for renovations. The move is been made by both retirees who find they can make their pension stretch a lot further and younger people looking for new business opportunities and finding it difficult to get on the property ladder in the UK.


EU Final word on Bulgaria to be known soon


Oli Rehn Gianluigi Buffon Italy Jersey , European Enlargement Commissioner is soon expected to present his report on Bulgaria Romania's accession to the EU in January 2007. It is generally believed that the planned memberships will go ahead however the accession treaty does contain a safeguard clause allowing membership to be postponed by one year if further reforms in each country are deemed necessary.


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